New study conducted by King’s College London researchers examines the way our bodies, specifically our brains, become “stress-resilient.” There is a significant variation in the way individuals react and respond to extreme stress and adversity—some individuals develop psychiatric conditions such as posttraumatic stress disorder (PTSD) or major depressive disorder (MDD) – others recover from stressful experiences without displaying significant symptoms of psychological ill-health, demonstrating stress-resilience.
To understand why some individuals exhibit characteristics of a resilient profile, the interplay between neurochemical, genetic, and epigenetic processes over time needs to be explained. In this review, the authors examine the hormones, neuropeptides, neurotransmitters, and neural circuits associated with resilience and vulnerability to stress-related disorders.
In conclusion the authors state, that an interdisciplinary approach combining neurobiological, genetic, epigenetic, and personality traits, as well community and group interactions, may work to facilitate the development of a stress-resilient profile. This in turn would be significant step toward the prevention and treatment of stress-related disorders such as PTSD or MDD.
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- Carlos Osório, Thomas Probert, Edgar Jones, Allan H. Young, Ian Robbins (2016). Adapting to Stress: Understanding the Neurobiology of Resilience. Behavioral Medicine, 1.